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IIIM-290 hyl isoeugenol InChi: InChI=1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5

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InChi: InChI=1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5

2015 Oct 5

InChi: InChI=1S/C25H25FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5

m-PEG11-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

6-48 hours) results in a remarkably time- and dose-dependent decrease in Cdc2 and Cdc25C expression levels and increases cyclin B1 within 6h

IIIM-290 hyl isoeugenol InChi: InChI=1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5IIIM 290 is a potent and oral CDK inhibitor with IC50s of 90 and 94 nM for CDK2 A and CDK9 T1. Product information CAS Number: 2213468 64 3 Molecular Weight: 462. 32 Formula: C23H21Cl2NO5 Chemical Name: 2 [(E) 2 (2,6 dichlorophenyl)ethenyl] 5,7 dihydroxy 8 [(3S,4R) 3 hydroxy 1 methylpiperidin 4 yl] 4H chromen 4 one Smiles: CN1C[C@@H](O)[C@H](CC1)C1=C2OC(=CC(=O)C2=C(O)C=C1O) C=C C1C(Cl)=CC=CC=1Cl InChiKey: NFTJDXGFOUFNKG UGBNQVSOSA N InChi: InChI=1S

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